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Our research focuses on developing protein modulators in order to study structure-function aspects of cellular protein networks and to develop new drugs targeting protein-protein interactions (PPIs) with both small molecules and optimized protein variants.

 

Drug discovery is a multidisciplinary science by nature and requires the understanding and application of biology, chemistry, pharmacology and biophysical tools.

Current Research Programs

  • Small-molecule modulators of disease-associated protein–protein interactions

  • Rationally engineered anti-inflammatory peptides for autoimmune disorders

  • Novel immunosuppressive strategies targeting calcineurin–NFAT signaling

  • Engineered protein therapeutics as next-generation non-antibody biologics

  • Engineering of bispecific proteins for dual targeting of cellular receptors

  • Natural protein bio-preservatives for antifungal food protection and shelf-life extension

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